The indicators in the report present a synthesis of research and innovation performance in Italy. They relate knowledge investment and input to performance and economic output throughout the innovation cycle. They show thematic strengths in key technologies and also the high-tech and medium-tech contribution to the trade balance. The indicator on excellence in science and technology takes into consideration the quality of scientific production as well as technological development. The Innovation Output Indicator covers technological innovation, skills in knowledge-intensive activities, the competitiveness of knowledge-intensive goods and services, and the innovativeness of fast-growing enterprises, focusing on innovation output. The indicator on knowledge-intensity of the economy focuses on the economy’s sectoral composition and specialisation and shows the evolution of the weight of knowledge-intensive sectors and products.